| Publication Type: | Journal Article |
| Year of Publication: | 2010 |
| Authors: | Wansi, JDuplex, Hussain, H, Tcho, ATadjong, Kouam, SF, Specht, S, Sarite, SRamadan, Hoerauf, A, Krohn, K |
| Journal: | Phytotherapy Research |
| Volume: | 24 |
| Issue: | 5 |
| Date Published: | 2010 |
| ISBN Number: | 1099-1573 |
| Keywords: | antiplasmodial activity, furoquinoline alkaloids, Rutaceae, Teclea afzelii |
| Abstract: | The study of the chemical constituents of the stem bark of Teclea afzelii (Rutaceae) has resulted in the isolation and characterization of four furoquinoline alkaloids, namely kokusaginine (1), tecleaverdoornine (2), maculine (3) and montrifoline (4) together with lupeol (5) and b-sitosterol glucopyranoside (6). The structures of the isolated compounds were elucidated based on spectroscopic studies. The antimalarial activity of compounds 1–4 against Plasmodium falciparum in vitro shows partial suppression of parasitic growth. Copyright © 2009 John Wiley & Sons, Ltd. |
| URL: | http://dx.doi.org/10.1002/ptr.2894 |
| Short Title: | Phytotherapy Research |
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